C-F insertion reaction sheds new light on the construction of fluorinated compounds

Dong-Sheng Deng, Su-Qin Tang, Yong-Tu Yuan, Ding-Xiong Xie,Zhi-Yuan Zhu, Yue-Mei Huang,Yun-Lin Liu

Chinese Chemical Letters(2023)

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摘要
The atom-economical C-F insertion chemistry is emerged as a promising technology for the synthesis of various fluorinated scaffolds, which have wide applications both in the academic and the industrial communities. The past three years have witnessed rapid developments in this field. This highlight provides an overview on the evolution according to the fluorinating agents used.
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关键词
C-F insertion,Benzyl fluoride,Acyl fluoride,Gem-difluorocyclopropane,Fluorinated scaffold
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