Increased intracranial pressure in acute bacterial meningitis.

Christine Lodberg Hvas,Åse Bengård Andersen,Kirsten Møller, Klaus Hansen,Frantz Rom Poulsen, Christian Overgaard-Steensen

Ugeskrift for laeger(2023)

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摘要
Acute bacterial meningitis (ABM) is associated with increased intracranial pressure (ICP) caused by bacterial invasion and the host response to infection. Antibiotic therapy is a sine qua non, and adjunct dexamethasone decreases mortality. The ICP increase may have a rapid course and death due to herniation is most often seen within the first week. Evidence regarding treatment of increased ICP in ABM is limited; this review summarises observational studies which point towards reduced mortality by applying a structured approach towards normalization of ICP in ABM.
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