[Interferon-α mediating the functional damage of CD56 dim CD57 + natural killer cells in peripheral blood of systemic lupus erythematosuss].

Xiang Ge Zhao,Jia Qing Liu, Hui Na Huang,Zhi Min Lu,Zi Ran Bai,Xia Li,Jing Jing Qi

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences（2023）

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摘要

High serum IFN-α level in SLE patients may induce apoptosis by promoting mtROS production and inhibit perforin expression, which can down-regulate CD56CD57 NK killing function.

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