Periplaneta americana extract attenuates hepatic fibrosis progression by inhibiting collagen synthesis and regulating the TGF-β1/Smad signaling pathway.

Yi Chen,Yanwen Zhao,Liping Yuan, Ying He,Yongshou Yang,Peiyun Xiao

Folia histochemica et cytobiologica（2023）

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摘要

The therapeutic effect of PA-B on liver fibrosis might involve suppression of the secretion and expression of TGF-β1, regulation of the TGF-β1/Smad signaling pathway, and inhibition of collagen production and secretion.

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