Gleason score 3+3[6 prostatic adenocarcinoma is not benign and the current debate is unhelpful to clinicians and patients

PATHOLOGY(2024)

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摘要
Prostate adenocarcinoma is a common malignancy associated with a significant morbidity and mortality. In both prostate biopsies and radical prostatectomy specioutcome prediction. The current convention is that in needle biopsies, Gleason patterns 3, 4 and 5 are considered to be malignant. Despite this there is debate as to whether or not Gleason score (GS) 3+3=6 should be diagnosed as cancer due to potential over-treatment and the psychological impact on patients. It is apparent that GS 3+3=6 is indolent disease with a low risk of metastasis. cludes Gleason patterns of higher grade? This would 3 component in cancers with multiple patterns are 4+5=9, 5+4=9 and 5+5=10 which is clearly inappropriate. reclassify malignant tumours as benign.
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关键词
Prostate,adenocarcinoma,Gleason score,prognosis
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