In vitro activity of clindamycin, doxycycline, and trimethoprim/sulfamethoxazole against clinical isolates of β-hemolytic Streptococcus spp. via BD Phoenix and broth microdilution.

Christian Cho,Ryan K Shields,Ellen G Kline,Thomas L Walsh,Chelsea E Jones,Karen Kasarda,Kelly Stefano,Matthew A Moffa,Derek N Bremmer

Antimicrobial Stewardship & Healthcare Epidemiology（2023）

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摘要

We tested 85 isolates of β-hemolytic Streptococcus spp. against trimethoprim/sulfamethoxazole (TMP/SMX), clindamycin, and doxycycline by broth microdilution (BMD) and BD Phoenix. Susceptibility rates via BMD for TMP/SMX, clindamycin, and doxycycline were 100%, 85.5%, and 56.6%, respectively. TMP/SMX is a potential monotherapy agent for β-hemolytic Streptococcus skin and soft tissue infections.

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