Nanobodies to Multiple Spike Variants and Inhalation of Nanobody-Containing Aerosols Neutralize SARS-CoV-2 in Cell Culture and Hamsters

Metin Aksu,Priya Kumar,Thomas Guettler,Waltraud Taxer,Kathrin Gregor,Bianka Mussil, Oleh Rymarenko,Kim M. Stegmann,Antje Dickmanns, Sabrina Gerber,Wencke Reineking,Claudia Schulz,Timo Henneck, Ahmed Mohamed,Gerhard Pohlmann, Mehmet Ramazanoglu,Kemal Mese,Uwe Gross, Tamar Ben-Yedidia, Oded Ovadia, Dalit Weinstein Fischeri, Merav Kamensky, Amir Reichman,Wolfgang Baumgartner,Maren von Koeckritz-Blickwede,Matthias Dobbelstein,Dirk Goerlich

ANTIVIRAL RESEARCH（2024）

引用 5|浏览26

关键词

SARS-CoV-2,Variants of concern,Spike,Receptor binding domain,Nanobodies,VHH antibodies,Protein structure,Inhalation,Aerosol,COVID-19,Animal model,Hamster

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