Optometry in adults with microdeletion 22q11.2: The eye as a window to the brain

Emma N.M.M. von Scheibler,Abhishek Appaji,Tos T.J.M. Berendschot,Noël J.C. Bauer,Naren P. Rao,Agnies M. van Eeghen,Thérèse A.M.J. van Amelsvoort,Erik Boot

Biomarkers in Neuropsychiatry（2023）

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摘要

•Higher fractal dimension and tortuosity in microdeletion 22q11.2 than in controls.•Decrease of fractal dimension with age in microdeletion 22q11.2 only.•Nerve fiber layer thickness decreased with age in microdeletion 22q11.2 only.•Retinovascular imaging: potential biomarker for psychosis in microdeletion 22q11.2.•Fractal dimension and nerve fiber layer thickness biomarkers for neurodegeneration?

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关键词

22q11.2 deletion syndrome,Fundoscopy,Optical coherence tomography,Neurodegeneration,Microvasculature

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