Cytotoxic Th1 cells mushroom after fungal exposures in Crohn's disease

Martin Strazar,Ramnik J. Xavier

IMMUNITY(2023)

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摘要
Fungi are consistently enriched in inflamed intestines, with elusive effects on host immunity. In a recent issue of Nature Medicine, Martini et al. identify a subset of Th1 cells able to lyse the epithelium, enriched in Crohn's disease patient samples after fungal exposure.
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