Unlocking the EGFR-mediated epitranscriptome A pathway to novel therapies
MOLECULAR CELL（2023）
摘要
In this issue, Lv et al.(1) explore EGFR-driven epitranscriptomic reprogramming in glioblastoma, revealing the pivotal role of the EGFR-ALKBH5-GCLM axis in ferroptosis protection. Their findings offer mechanistic insight and therapeutic strategies involving novel combination targets to enhance tumor responses.
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