1-(3-(2-(Dimethylammonio)ethyl)-1H-indol-5-yl)- N-Methylmethanesulfonamide Succinate Hemi(Ethanol Solvate)

Petr A. Buikin,Anna V. Vologzhanina, Alexander A. Korlyukov

crossref(2023)

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摘要
Sumatriptan is a serotonin receptor agonist approved by FDA in 1992 to treat migraines. Its’ solid form used in commercially available drugs Imitrex, Treximet, Onzetra Xsail and Zembrace symtouch is sumatriptan succinate. Herein we report on crystal structure of sumatriptane succinate hemi(ethanol solvate), HSum+·HSucc–·0.5EtOH, its comparison with previously reported solids containing derivatives of sumatriptan.
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