Malignant spinal cord compression

Ana Šešek,Barbara Šegedin

Onkologija(2023)

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摘要
Malignant spinal cord compression is one of the most serious complications of cancer and represents an oncologic emergency. Timely diagnosis and treatment within 24 hours of symptom onset affects disease outcome and patient’s quality of life. Most of the patients that present with spinal cord compression have a known diagnosis of cancer, yet in some of them spinal cord compression is the first clinical manifestation of the disease. Most cases of spinal cord compression are the result of tumour growth from the vertebral body into the spinal canal, dislocation of bone fragments, intramedullary and leptomeningeal metastases are less frequent causes of spinal cord compression. The most common site of malignant spinal cord compression is the thoracic spine. Back pain is the first symptom in majority of patients, later sensory and/or motor deficits and loss of sphincter control can occur. Magnetic resonance imaging of the whole spine is the gold standard in the diagnostic of malignant spinal cord compression. Radiotherapy with or without surgery is the most common treatment approach. We present a case of a patient with prostate cancer with known bone metastases and spinal cord compression.
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关键词
spinal cord compression,radiotherapy,paresis,prostate cancer
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