Diuretics Therapy

Thiazide-type diuretics are one of the most important antihypertensive classes in the management of hypertension. They are one of the preferred antihypertensive classes for therapy of hypertension according to treatment guidelines, and are a foundational piece of most successful antihypertensive drug regimens. If they are not the initial agent, they should clearly be added when blood pressure goals have not been achieved because they provide synergy in lowering blood pressure to nearly all other antihypertensive classes. Careful attention to dosing and individual patient characteristics can ensure that adverse effects remain minimal and manageable.