HEMERA 1 CarboxyHEMoglobin OxygEn delivery for Revascularization in Acute Stroke: Phase 1 Clinical T

Italo Linfante,Wayne M. Clark, Diogo Houssen,Ricardó A. Hanel,Rwoof Reshi,Guilherme Dabus,Marilyn J. Cipolla, David Lieberskind,Raul G Nogueira

The Arab journal of interventional radiology（2023）

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摘要

Introduction: A polyethylene glycol hemoglobin-based oxygen carrier (HBOC) in the carboxy state (PP-007) has shown to increases blood flow in leptomeningeal anastomosis and decrease final infarct volume in rat models of middle cerebral artery occlusion. PP-007 may deliver more oxygen than Hb contained in RBCs.

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acute stroke,oxygen delivery,revascularization

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