Aberrant Early-Life Gut Microbial Maturation in Childhood Asthma

Kathleen Lee-Sarwar, Yih‐Chieh Chen,Yulu Chen,Jessica Lasky‐Su,Rachel S. Kelly,Jakob Stokholm,Hans Bisgaard,Klaus Bønnelykke, Casper Pedersen,Bo Chawes,Nancy Laranjo,Scott T. Weiss,Augusto A. Litonjua

The Journal of Allergy and Clinical Immunology（2023）

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摘要

Environmental, genetic, and microbial factors are independently associated with childhood asthma. We aimed to determine the roles of environmental exposures and 17q21 locus genotype in the maturation of the early-life microbiome in childhood asthma.

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childhood asthma,early-life

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