Differential Cellular Responses to FDA-Approved Nanomedicines: An Exploration of Albumin-Based Nanocarriers and Liposomes in Protein Corona Formation

Athika Darumas Putri,Ming Jen Hsu, Chih-Ping Han,Fang-Ching Chao,Chun‐Hua Hsu,Christian D. Lorenz,Chien Ming Hsieh

Nanoscale（2023）

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摘要

Albumin nanoparticles attract less serum protein adsorption than liposomes and hard corona proteins on albumin nanoparticles elicit higher cellular uptake. Coarse-grained molecular simulations reveal the biological mechanism of protein corona.

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关键词

nanomedicines,nanocarriers,liposomes,fda-approved,albumin-based

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