Switchable Hydrophilicity Solvents (SHSs) in Green Sample Preparation

In the year 2005, an important class of solvents was introduced to the scientific community by the Dr Philip G. Jessop team: namely, switchable hydrophilicity solvents (SHSs). Given their valuable characteristics, such as easy application, effectiveness, and compatibility with various microextraction techniques, in addition to their being environmentally friendly, SHSs have gained visibility in sample preparation, especially in recent years. Running through the history of their applications, this chapter covers the use of SHSs in green sample preparation, where their advantages are discussed, highlighted, and compared with other well-known strategies. Applications dealing with parameters commonly optimized in techniques that use SHSs, mainly in environmental and food analysis, are presented.