Tetrahydrocannabinol and Cannabidiol in Tourette Syndrome.

Philip E Mosley, Lachlan Webb,Anastasia Suraev, Leah Hingston, Tracy Turnbull, Kelley Foster, Emma Ballard, Lauren Gomes,Adith Mohan,Perminder S Sachdev,Richard Kevin, Rebecca Gordon,Melissa Benson,Iain S McGregor

NEJM evidence（2023）

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摘要

Tetrahydrocannabinol and Cannabidiol in Tourette SyndromeThis randomized controlled crossover trial examined the use of oral tetrahydrocannabinol (THC) with cannabidiol (CBD) to reduce tics in patients with severe Tourette syndrome. Treatment with THC and CBD for 6 weeks led to a significant reduction in tics as measured by the total tic score on the Yale Global Tic Severity Scale, without major adverse effects.

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关键词

tetrahydrocannabinol,tourette syndrome,cannabidiol

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