EP02.01-06 TP53 Mutation Has Significant Impact on Other Driver Genes in Lung Cancer

Y. Yang, H. Wang,H. Wang, W. Fan, B. Lian, Y. Jin, W. Luo, J. Mao, Y. Feng, Z. Long, H. Xie, M. Huang, L. Zheng, Z. Pan, M. Huang, Y. Wang, Y. Wen,J. Huang

Journal of Thoracic Oncology（2023）

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摘要

TP53 is the most commonly mutated driver gene in cancer, studies assessing the functions of TP53 and its potential implications are of paramount importance. We sought to determine genetic characteristic of TP53 with respect to cancer-related co-mutations and their correlation with TMB.

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关键词

tp53 mutation,lung cancer,other driver genes

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