Engineering of Uniform Epidermal Layers via Sacrificial Gelatin Bioink‐Assisted 3D Extrusion Bioprinting of Skin (Adv. Healthcare Mater. 27/2023)

Advanced Healthcare Materials(2023)

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摘要
Extrusion Bioprinting Article 2301015 by Ge Gao, Dong-Woo Cho, Byoung Soo Kim, and co-workers highlights the first study to use sacrificial gelatin-assisted extrusion bioprinting to reproduce a uniform and stratified epidermal layer. Various evaluations, including rheological properties, bioprintability. cell viability, initial adhesion of keratinocytes, and finally dermal–epidermal maturation are demonstrated to show the potential of our methodology. The findings reveal that the gelatin-assisted approach is advantageous for recreating reliable full-thickness skin models with significant consistency for mass production.
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关键词
uniform epidermal layers,skin,gelatin
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