FLUIDOT: A Modular Microfluidic Platform for Single‐Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining (Small Methods 3/2023)

Jolien Breukers,Karen Ven,Caroline Struyfs, Louanne Ampofo,Iene Rutten,Maya Imbrechts, Francesca Pollet,Julie Van Lent,Winnie Kerstens,Sam Noppen,Dominique Schols,Paul De Munter,Hendrik Jan Thibaut,Karen Vanhoorelbeke,Dragana Spasić,Paul Declerck,Bruno P. A. Cammue,Nick Geukens,Karin Thevissen,Jeroen Lammertyn

Small Methods（2023）

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摘要

Front Cover In article number 2201477, Lammertyn and co-workers developed FLUIDOT, a modular microfluidic platform in which microwells, optical tweezers, and an interchangeable cell-retrieval system are combined to enable in-depth screening and specific retrieval of single cells. They demonstrated the versatility of FLUIDOT by implementing applications in drug tolerance screening and antibody mining. The cover was designed by Jorik Waeterschoot.

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关键词

modular microfluidic platform,antibody mining,drug tolerance screening,single‐cell

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