Antibacterial effects against pathogens of Vibrio genus using 5-aminolevulinic acid produced from recombinant Escherichia coli

Yi-Chieh Liao,Yung-Chung Lo,Ngai Hei Ernest Ho,Duu-Jong Lee,I-Son Ng,Jo-Shu Chang

Journal of The Taiwan Institute of Chemical Engineers（2023）

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摘要

•5-ALA demonstrated growth inhibition in three vibrio species found in aquaculture.•Antimicrobial photodynamic therapy against vibrio spp. was more effective at pH 4.5.•5-ALA exhibited antimicrobial activity under both light and dark conditions.•The optimal activity of 5-ALA under dark condition occurred with a 2 h exposure at pH 7.•Both crude and pure 5-ALA exhibited similar antimicrobial effects against vibrio species.

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关键词

Vibrio parahaemolyticus,Vibrio alginolyticus,5-aminolevulinic acid,Antimicrobial photodynamic therapy,Bactericidal effect

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