Nonsurgical Interventions to Prevent Disease Progression in Prostate Cancer Patients on Active Surveillance: A Systematic Review and Meta-analysis

Akihiro Matsukawa,Takafumi Yanagisawa,Kensuke Bekku,Mehdi Kardoust Parizi,Ekaterina Laukhtina,Jakob Klemm,Sever Chiujdea,Keiichiro Mori,Shoji Kimura,Jun Miki,Benjamin Pradere,Juan Gomez Rivas,Giorgio Gandaglia,Takahiro Kimura,Veeru Kasivisvanathan,Guillaume Ploussard,Philip Cornford,Shahrokh F. Shariat,Pawel Rajwa

European Urology Oncology（2023）

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摘要

We found that 5-alpha reductase inhibitors can delay progression in men with prostate cancer undergoing active surveillance (AS). Certain anticancer drugs, such as chlormadinone, fexapotide triflutate, and enzalutamide, demonstrated effectiveness; however, these therapies are associated with significant treatment-related adverse events, limiting their use in the setting of AS.

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关键词

Prostate cancer,Active surveillance,5-Alpha reductase inhibitor,Statin,Diet,Exercise,Coffee,Vitamin D3,PROSTVAC

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