Correlation of Maternal Blood Glucose Level to Maternal Delivery and Fetal Outcome in Hasan Sadikin General Hospital

Increase of blood glucose level In pregnant woman correlated with increased risk of maternal morbidity, and problems in labour also affect child outcome. This phenomena cause by physiological changes occur in pregnancy such as placental factor and inflammation factor in circulation. Changes in inflammation factor like tumor nerosis factor (TNF-α) and beta-cell correlated gene disfunction (potassium voltage-gated channel KQT-like 1 (Kcnq1) and glucokinase (Gck)) could affect blood glucose level. Blood glucose control in pregnant woman known to be effective to decrease and prevent complication in mother and fetus, such as preeclampsia, prematurity, low birth weight, and asphyxia baby. This research wish to know correlation of maternal blood glucose level to maternal delivery and fetal outcome. This research use seconder data from medical records as retrospective cohort study. Subject of this study are pregnant mother which given birth in Hasan Sadikin Hospital (RSHS) sbetween January 2018 – December 2021 and has been performed blood glucose test when first time administered in Hasan Sadikin Hospital. Analitic statistic was performed with contingency correlation test, association test with chi-square and continued with multivariate logistic regression. From 8996 subjects, positive correlation was founded between high random blood glucose with preeclampsia (r=0.154, p<0.001), premature labour (r=0.020, p=0.052), and low birth weight (r= -0.034, p=0.003). Correlation between random blood glucose and asphyxia was unfounded (r=0.003, p=0.809). There’s weak positive correlation between random blood glucose to preeclampsia and prematurity incidence. There’s also weak negative correlation between random blood glucose and baby birth weight. Correlation between blood glucose and APGAR score was unfounded.