Evaluation of single-strain Prevotella histicola on KLH-driven immune responses in healthy volunteers: A randomized controlled trial with EDP1815

Mahdi Saghari, Pim Gal, Hendrika W. Grievink, Erica S. Klaassen, Ahnjili Zhuparris, Andrea Itano,Mark Bodmer,Duncan McHale,Matthijs Moerland

Medicine in Microecology（2024）

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摘要

•Evidence suggests that intestinal microbiota can interact with the immune system.•EDP1815 (single-strain P. histicola microbe) shows promising preclinical immunomodulatory effects.•KLH-driven immune responses were overall lower in EDP1815-treated volunteers.•Based on the EDP1815 data at hand more research is needed.

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关键词

immune responses,single-strain,klh-driven

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