COMPARAÇÃO DE ACHADOS HISTOPATOLÓGICOS EM PLACENTAS DE PARTURIENTES INFECTADAS OU NÃO POR SARS-CoV-2

Objectives: It is not clear whether COVID-19 has any effect on the placenta or even impacts pregnancy outcomes. The aim was to compare the histomorphological characteristics of placentas from parturients with positive and negative PCR for SARS-CoV-2. Methods: Cross-sectional study from May 2021 to March 2022 where histopathological analysis of placentas from women who underwent PCR for the diagnosis of COVID-19, were performed using the Hematoxylin/Eosin staining method. Results: The sample consisted of placentas from thirty parturients, among which ten had been diagnosed with COVID-19 confirmed by PCR (33.3%). Results revealed higher levels of congestion, chronic focal villitis and acute funisitis in placentas from parturients diagnosed with COVID-19. Negative parturients had a higher percentage of intervillous hemorrhage with thrombus formation, dystrophic calcification, placental infarction, and capsular acute deciduitis. Conclusion: No unusual placental histopathological pattern was found among women with positive PCR for SARS-CoV-2. Observational studies with larger samples are warranted.