Organocatalytic Enantio‐ and Diastereoselective Diels‐Alder Reaction between 2,4‐Dienals and α,β‐Unsaturated Esters.

The inside cover picture illustrates a starship satellite for the asymmetric Diels–Alder reaction between 2,4-dienals and various α,β-unsaturated esters in the organocatalytic universe. Leveraging the power of organocatalysis, the catalytic process facilitates the creation of a diverse range of densely functionalized cyclohexenes bearing multiple stereogenic centers with high levels of stereoselectivity (up to >20:1 dr and >99% ee). Details can be found in the Research Article by Sarah Yunmi Lee and co-workers. (B. Kim, S. Lee, S. Y. Lee, Adv. Synth. Catal. 2023, 365, XXXX–XXXX; DOI: 10.1002/adsc.202300756)