Impact of exercise on markers of B cell-related immunity: A systematic review

•Markers of B cell-related immunity are altered by acute exercise and exercise training.•B cell counts and levels of secretory and plasma immunoglobulin A are among the most exercise-responsive markers.•The large heterogeneity concerning study populations and exercise regimens and the poor study quality and reporting of results hamper evidence-based conclusions on the impact of exercise on B cell-related immunity.•Alternative markers (e.g., immunoglobulin free light chains), subpopulations of B cells and functional outcomes of B cell-related immunity should be included more frequently in future exercise studies.