Long-Term Blood Pressure Variability and Cortical Thickness in Older Adults

D.H. Gutteridge, A. Segal,John J McNeil,Lawrence J. Beilin,Amy Brodtmann, E. Chowdhury,Gary F. Egan,Michael E. Ernst, Malik Asif Hussain, C. Reid,Catherine Robb,Joanne Ryan,Robyn L. Woods,Hannah A.D. Keage,Sharna Jamadar

Heart, Lung and Circulation（2023）

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摘要

High blood pressure variability (BPV) is a risk factor for cognitive decline and dementia, but its association with cortical thickness is not well understood. This study used a topographical approach, via the Desikan–Killiany atlas, to assess links between long-term BPV and cortical thickness in 478 (54% male at baseline) community dwelling older adults (70–88 years) from the ASPirin in Reducing Events in the Elderly (ASPREE) NEURO sub-study.

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blood pressure,cortical thickness,older adults,long-term

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