Longitudinal Assessment of Left Ventricle Systolic Function in Acute Myocardial Infarction Patients Post Percutaneous Coronary Intervention

Abstract Purpose: The present study aimed to longitudinally evaluate LV systolic function among patients who underwent primary PCI for acute MI on the basis of culprit vessel. Methods: A Cohort study was conducted involving 258 patients who underwent primary angioplasty for Acute MI. Each participant underwent an initial echocardiography assessment using a range of methods, including M-mode and two-dimensional measurements, as well as strain and strain rate parameters. Subjects were followed up for a period of one month to assess the LV systolic function. Results: A significant improvement in LV global strain noted after one month of revascularization (p value=0.013). A significant decrease in Left ventricular global longitudinal strain (LV GLS) value is noted in patients who had major adverse cardiac events (MACE) when compare to event free group. Wall motion score index value and LV end systolic volume were significantly higher in MACE category than event free category. Conclusion: A study demonstrated an enhancement in left ventricular (LV) systolic function,when measured using Speckle tracking echocardiography than LVEF irrespective of culprit vessel. MACE occurred in 4.3% of Acute MI patients even after successful PCI. The Baseline LV EF and Wall motion score index was proved to be independent predictor of Major adverse cardiac events at one-month follow-up than LV strain.