Dietary Lactobacillus rhamnosus GG extracellular vesicles enhance anti-PD-1 immunotherapy efficacy against colorectal cancer

Lu Shen, Jianming Xu, Zhao Zhen, Yunli Guo, Hanwen Zhang,Peter W. Jurutka,Dechun Huang,Chongjiang Cao,Shujie Cheng

Food & Function（2023）

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摘要

Dietary Lactobacillus rhamnosus GG extracellular vesicles (LGG-EV) synergistically enhanced anti-PD-1 immunotherapy efficacy against colorectal cancer. It was associated with improved tumor immunosuppressive environment, the abundance of beneficial bacteria and elevated specific serum metabolites.

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关键词

colorectal cancer,extracellular vesicles,immunotherapy

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