Identification of an Arylnaphthalene Lignan Derivative as an Inhibitor against Dengue Virus Serotypes 1 to 4 (DENV-1 to -4) Using a Newly Developed DENV-3 Infectious Clone and Replicon

Mingyue Hu,Wanfei Li,Tiantian Wu,Yang Yang,Guoquan Chen,Tongling Chen,Yongchen Liu, Ya-Fang Mei,De Wu,Youchuan Wei,Ting Luo,Hongjie Zhang,Yi-Ping Li

Microbiology spectrum（2023）

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摘要

Dengue virus (DENV) is the most prevalent mosquito-transmitted virus, and there is no an anti-dengue drug. Reverse genetic systems representative of different serotype viruses are invaluable tools for the study of viral pathogenesis and antiviral drugs.

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arylnaphthalene lignan derivative,dengue virus serotypes

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