Effect of pneumovesicoscopic Cohen surgery with adjustable suspension technique through natural channel on the treatment of primary vesicouretral reflux disease in infants

Abstract Objective: The objective of this study was to evaluate the safety and efficacy of pneumovesicoscopic Cohen surgery with adjustable suspension technique through natural channel on the treatment of primary vesicouretral reflux disease in infants. Methods: This study retrospectively analyzed the clinical data of 31 infants who underwent pneumovesicoscopic Cohen surgery with adjustable suspension technique through natural channel in our hospital from January 2019 to December 2020. We also collected the clinical data of 29 infants who underwent open Cohen surgery in our hospital from January 2015 to December 2018 as a control. The clinical efficacy of the two groups was compared. Result: All the pneumovesicoscopic Cohen surgery were successfully completed, and no one transferred to open surgery. The amount of bleeding, duration of postoperative analgesic, duration of postoperative hematuria, incision size and length of hospital stay in the pneumovesicoscopic surgery group were significantly lower than those in the open surgery group (P<0.05). The operation time of pneumovesicoscopic surgery group was significantly longer than that of open surgery group (P<0.05). Both groups were followed up 6 months after surgery. At the 6 months follow-up time, there were no significant differences in the degree of hydronephrosis, renal scar, renal atrophy, glomerular filtration rate, KIM-1 and MCP-1 expression between the two groups (P>0.05). Conclusion: Pneumovesicoscopic Cohen surgery with adjustable suspension technique through natural channel on the treatment of primary vesicouretral reflux disease in infants was safe and effective, it had the advantages of less trauma, quick recovery and good cosmetic effect.