Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography

Catherine Grace Fitzgerald Dickmann,Alex McDonald,Nhi Huynh, Li Wang, M. A. Parker,Hui Gan,Andrew R. Scott,Ingrid Burvenich,Uwe Ackermann,Jonathan M. White,Angela Rigopoulos,Nancy Guo,Laura Ossellame,Zhanqi Liu

Chemical Communications（2023）

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摘要

A fluorine-18 labelled probe was developed to target bromodomain and extraterminal (BET) proteins for molecular imaging of cancer with positron emission tomography.

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关键词

positron emission tomography,tumour visualisation,protein-targeted

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