Enteric and non-enteric adenoviruses in children with acute gastroenteritis in Western India
Authorea (Authorea)(2023)
摘要
Human adenoviruses (HAdVs) are among the most important etiological agents of acute gastroenteritis (AGE). HAdVs found in 5.2% of children admitted for AGE between 2013 and 2016 in seven different hospitals across four cities of Western India. The dominance of subgroup-F (52.4%) strains was observed, followed by the occurrence of non-enteric adenoviruses of the subgroup A (17.4%), C (11.4%), B (8.2%), and D (3.2%). The subgroup-F strains were predominant in Ahmadabad (78.5%), Mumbai (61.5%), and Surat (57.1%) cities, followed by subgroup A strains. In Pune city, subgroup B and C strains were detected in 62.5% of AGE patients, with none of the subgroup A strains. Clinically, patients infected with enteric and non-enteric HAdV strains were indistinguishable from each other. However, a high viral load was observed in subgroup-F specimens as compared to non-subgroup-F. The study highlights the need for viral load estimation to ascertain the role of enteric and non-enteric HAdV strains associated with diarrheal etiology.
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关键词
acute gastroenteritis,non-enteric
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