MTHFR mutation: Another unifying etiology of chronic overlapping pain conditions

Joseph Visingardi, Jan A. Paredes Mogica,Padma Sundaram, Talia Denis, Courtney Bellomo, Artem Loktev, Charles Argoff,Elise J.B. De

Continence（2023）

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摘要

•MTHFR mutations can be associated with chronic pain syndromes.•This mutation may affect folate metabolism pathways, hindering the ability to maintain nerve function over time.•MTHFR may serve a unifying role in a subset of complex chronic pelvic pain patients.

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关键词

Pelvic pain,Small fiber neuropathy,Methylenetetrahydrofolate reductase

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