Self-Propelled Proteomotors with Active Cell-Free mtDNA Clearance for Enhanced Therapy of Sepsis-Associated Acute Lung Injury (Adv. Sci. 27/2023)

Weichang Huang, Lihong Wen,Hao Tian,Jiamiao Jiang,Meihuan Liu,Yicheng Ye,Junbin Gao,Ruotian Zhang,Fei Wang,Huaan Li,Lihan Shen,Fei Peng,Yingfeng Tu

Advanced Science（2023）

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摘要

Self-Propelled Proteomotors with active cf-mtDNA ClearanceIn article number 2301635, Lihan Shen, Fei Peng, Yingfeng Tu, and co-workers develop a novel DNase-I-powered nanomotor system which efficiently eliminates cf-mtDNA and inhibits TLR9-mediated inflammatory activation of alveolar macrophages as a novel strategy for sepsis-associated acute lung injury treatment.image

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proteomotors,sepsis‐associated,lung

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