Cover Feature: Optimization of the Lead Compound NVP‐BHG712 as a Colorectal Cancer Inhibitor (Chem. Eur. J. 23/2023)
Chemistry - A European Journal(2023)
摘要
Novel inhibitors that target the Eph family of transmembrane tyrosine kinase receptors have been optimized and characterized. Some of the compounds show remarkable receptor selectivity and affinity for the Eph receptors and inhibit the growth of colon cancer cells where these receptors are expressed and active. More information can be found in the Research Article by G. Tosato, H. Schwalbe and co-workers (DOI: 10.1002/chem.202203967).
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关键词
colorectal cancer inhibitor,colorectal cancer,nvp‐bhg712,lead,compound
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