Poor response to sorafenib in HCC patients induces distinct immune-related signatures and is mediated by hypoxia-related 14-3-3 scaffolding proteins

Jovana Castven,Diana Becker, S. Heinrich,Carolin Zimpel,Darko Castven, BeateKatharina Straub,Peter Grimminger, P Galle,Arndt Weinmann, J. Marquardt

Zeitschrift Fur Gastroenterologie（2023）

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摘要

Introduction Poor response to the drug treatment or relapse quickly after initial remission are events frequently observed in an advanced stage of hepatocellular carcinoma (HCC).

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关键词

sorafenib,hcc patients,immune-related,hypoxia-related

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