Authors' response

Dr Weinberger, in his correspondence, 1 Weinberger M. Chronic cough is complicated. Ann Allery Asthma Immunol. 2023; 131: 280 Google Scholar is correct that the management of chronic cough can be complicated, especially if up-to-date evidence-based guidelines, based on high-quality systematic reviews, are not followed. Chronic cough is complicatedAnnals of Allergy, Asthma & ImmunologyVol. 131Issue 2PreviewIrwin et al1 provide an extensive review of acute and chronic cough. The review states that “following a systematic protocol should lead to favorable outcome 90% of the time.” However, other reviews suggest that more than 40% of patients with chronic cough presenting to specialty cough centers are without a diagnosis.2 Moreover, idiopathic chronic cough has been described as a distinct clinical entity without a pathologic explanation or defined treatment.3 Frustration is therefore all too common among clinicians faced with a patient who has chronic cough but no explanation despite careful evaluation and therapeutic trials. Full-Text PDF