In vitro efficacy of direct oral anticoagulants in plasma from patients with liver cirrhosis

C Portela Pereira,MG Zermatten, Monserrat Fraga,Debora Bertaggia Calderara,Alessandro Aliotta, L. Veuthey, D. Shehwar,Darius Moradpour,Lorenzo Alberio

Hamostaseologie（2023）

引用 0|浏览4

暂无评分

摘要

Introduction Liver cirrhosis (LC) is a complex pathology which confers a prothrombotic state. The anticoagulation of LC-patients remains challenging because of the unknown efficacy of heparins and direct oral anticoagulants (DOAC), monitoring difficulty (particularly for coumarins), and alterations in drug metabolism. Here, we aimed to analyse the in vitro efficacy of DOAC (apixaban, edoxaban, rivaroxaban, and dabigatran) in LC-patients’ plasma.

查看译文

关键词

direct oral anticoagulants,liver cirrhosis,vitro efficacy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要