Abraham model solute descriptors for two additional α-amino acids: D-Tryptophan and L-Tyrosine

ABSTRACTAbraham model solute descriptors have been determined for the zwitterionic forms of D-tryptophan and L-tyrosine based on published mole fraction solubility data. The calculated solute descriptors describe the observed solubility data to within standard errors of 0.122 log units (or less). Treatment of each amino acid as a non-zwitterionic molecular compound led to significantly larger standard errors than were observed for the zwitterion form.KEYWORDS: α-amino acidsAbraham modelsolute descriptorsmolar solubility ratioszwitterionic solutes AcknowledgmentsRamya Motati thanks the University of North Texas’s Texas Academy of Mathematics and Science (TAMS) program for providing a summer research scholarship award.Disclosure statementNo potential conflict of interest was reported by the authors.