Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT

(Cell 185, 4770–4787.e1–e8; December 8, 2022) We overlooked a related study that was published during the revision of the manuscript. This study visualized tubulin within immunoprecipitated TRiC complexes using cryo-EM and found partial tubulin density within the TRiC chamber similar to what we observe in Figure 4A (Kelly et al, 2022). We have now acknowledged this study in the Discussion and have cited it accordingly. We apologize for any confusion this error may have caused. Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCTGestaut et al.CellDecember 08, 2022In BriefStarting from unstructured tubulin bound to the chaperone prefoldin, the steps of TriC-guided tubulin folding are revealed in structural detail illuminating the folding mechanism. Full-Text PDF