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Abstract A32: GIGA-564, a Third Generation Anti-Ctla-4 with Minimal Ability to Block CTLA-4 Binding to B7 Ligands, Has Enhanced Efficacy but Reduced Toxicity Compared to Ipilimumab in Pre-Clinical Models

Erica L. Stone,Kyle P. Carter,Ellen K. Wagner,Michael A. Asensio,Emily Benzie,Yao Chiang,Garry L. Coles,Chelsea Edgar,Bishal K. Gautam,Ashley Gras,Jackson Leong,Renee Leong,Vishal A. Manickam,Rena A. Mizrahi,Ariel R. Niedecken,Jasmeen Saini,Savreet K. Sandhu,Jan Fredrick Simons,Kacy Stadtmiller,Brendan Tinsley,LaRee Tracy,Nicholas Wayham,Yoong Wearn Lim,Adam S. Adler,David S. Johnson

Cancer Immunology Research（2022）

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