Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus

Kaye Quizon, Kimberly Holloway, Mahmood Iranpour,Bryce M. Warner,Yvon Deschambault,Geoff Soule,Kevin Tierney,Darwyn Kobasa,Angela Sloan,David Safronetz

Emerging Infectious Diseases（2022）

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摘要

Abstract We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus mice, the established primary hosts for SNV.

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sin nombre virus,species rodents,experimental infection

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