Expression of Concern: Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs

Journal of Cell Science(2022)

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摘要
There are issues with J. Cell Sci. (2003) 116, 1905-1913 (doi:10.1242/jcs.00409).Background editing of the top Northern blot in Fig. 1 was reported anonymously to the journal. In addition, we identified splices in blots in several other figures. Owing to the period of time that has passed since experiments were conducted, original data are no longer available. However, many full blots for these figures are presented in the PhD thesis of the first author, revealing that most splices were made to excise empty lanes. The blurred blot in Fig. 1 is also present in the thesis, so we cannot determine whether blurring was introduced to obscure non-relevant bands between the two regions of interest.Both the first and last authors of the paper are deceased; The University of Dundee and authors for whom contact details were available (J.E.S., J.H., A.I.L.) were supportive of the investigation.The journal is publishing this note to alert readers to the issue with the blot in Fig. 1 and our efforts to resolve this.
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关键词
protein phosphatase,motor neurons complex,snrnps
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