Light-driven hydroxylation of testosterone by Synechocystis sp. PCC 6803 expressing the heterologous CYP450 monooxygenase CYP110D1

Francesco Mascia,Sara B. Pereira,Catarina C. Pacheco,Paulo Oliveira,Jennifer Solarczek,Anett Schallmey,Robert Kourist,Véronique Alphand,Paula Tamagnini

Green Chemistry（2022）

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摘要

Biotransformation of testosterone into 15β-hydroxytestosterone by the cyanobacterium Synechocystis expressing the heterologous monooxygenase CYP110D1. The reaction is sustained by reducing equivalents and oxygen provided by oxygenic photosynthesis.

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关键词

heterologous cyp450 monooxygenase,hydroxylation,testosterone,light-driven

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