Small Cell Lung Cancer

Lung cancer is the second most diagnosed cancer in the United States. It is the leading cause of cancer death in both men and women, accounting for approximately a quarter of all cancer deaths. Lung cancer is histologically divided into 2 main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). SCLC comprises about 15% of lung cancer while NSCLC comprises approximately 85%. Since the late 1980s, there has been a decline in the incidence of lung cancer coincident with a decline in smoking, the leading cause of lung cancer. Current treatments include surgery, chemotherapy, radiotherapy, and immunotherapy. The high incidence and prevalence of lung cancer provide a foundation for new insights into the role of public health interventions, genetics, and novel treatment modalities.