A New Thiohydantoin Derivative from the Roots of Lepidium meyenii

Macathiohydantoin S ( 1 ), a new thiohydantoin derivative, was isolated from the roots of Lepidium meyenii (Maca) collected from Qujing, Yunnan Province of China. The structure of 1 was elucidated on the basis of extensive spectroscopic data, including 1D NMR ( 1 H NMR, 13 C NMR), 2D NMR (HSQC, HMBC, and COSY) and HR-ESI-MS techniques. The cytotoxicities against five human cancer cell lines of compound 1 were also evaluated.