Which recipient factors influence time to find an oocyte donor match?

To identify recipient factors that influence the time to receive and accept an offer from a donor oocyte program at a single academic institution. Patients who became active on the potential donor oocyte recipient list between 1/1/2021 and 12/31/2021 were included. All potential donor oocyte recipients at our institution submitted a form documenting physical characteristics of the patient, including hair color, eye color, height, weight, as well as racial and ethnic information. If the patient had a partner, partner characteristics were also collected. Furthermore, patients could provide the clinic with additional features that they desired in an oocyte donor. These were grouped by requests related to physical features, ethnicity, personality, education, mental health history, family history, religion, talents, and prior pregnancy or donation success. When there was a suitable oocyte donor available, patients were provided with an offer and access to the oocyte donor profile. If the oocyte donor was accepted by the patient, they were considered matched. The primary outcomes were the time to first donor oocyte offer and time to first donor oocyte match. Kaplan-Meier survival analysis and univariate Cox regression were used to explore the relationship between offer time and patient demographics. A total of 122 patients were included in the study. The median patient age was 44.0 years at the time they joined the potential donor oocyte recipient list. In terms of patient race, 62.1% were white, 13.8% black or African American, 19.0% Asian, and 5.2% identified as some other race. 77.8% had one or more additional requests. Patients who identified as white received significantly more donor oocyte offers (P=.03), while patients who identified as Asian received fewer offers (P<.01). The estimated offer rate among Asian patients was 59% less than among non-Asians (HR .41, 95% CI .21-.79, P<.01). There were no significant differences in offer rates relative to the overall population for the other racial and ethnic groups (P=.8 for black or African American, P=.9 for Hispanic, P=.2 for two or more races). Additionally, patients with at least one prior cycle of autologous ovarian stimulation for in vitro fertilization had the same chance of receiving an offer (HR .74, 95% CI .45-1.21, P=.2) but took longer to accept an offer (P=.04). Their estimated acceptance rate was 44% less compared to those without prior autologous in vitro fertilization cycles (HR .56, 95% CI .32-.97, P=.04). No differences in donor oocyte offer and acceptance times were observed based on patient age, hair color, eye color, body mass index, or number of additional requests. Asian patients experience longer wait times for donor oocyte matches, while prior ovarian stimulation for autologous in vitro fertilization increases the time to accept an oocyte donor offer.